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IN VIVO METHODS OF MONITORING BIODISTRIBUTION
专利权人:
BOVIN, NIKOLAI VLADIMIROVICH;KORCHAGINA, ELENA YURIEVNA;BOVIN;HENRY, STEPHEN;TUZIKOV, ALEXANDER BORISOVICH; NIKOLAI VLADIMIROVICH;RODIONOV, IGOR LEONIDOVICH
发明人:
BOVIN, NIKOLAI VLADIMIROVICH,HENRY, STEPHEN,KORCHAGINA, ELENA YURIEVNA,RODIONOV, IGOR LEONIDOVICH,TUZIKOV, ALEXANDER BORISOVICH
申请号:
SG2013059399
公开号:
SG192623A1
申请日:
2012.02.09
申请国别(地区):
SG
年份:
2013
代理人:
摘要:
Functional-lipid constructs of the structure F-S-L are disclosed, wherein F comprises a tyrosine or histidine residue, S is a spacer covalently linking F to L and L is a lipid. The functional residue may be iodinated and used to radiolabel a biological entity with 1251 and the iodinated constructs are used in a non-invasive method of monitoring the distribution of a biological entity in vivo.
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