Stephen Henry;Nikolai Vladimirovich Bovin;Alexander Borisovich Tuzikov;Elena Yurievna Korchagina;Igor Leonidovich Rodionov
发明人:
Nikolai Vladimirovich Bovin,Stephen Henry,Elena Yurievna Korchagina,Igor Leonidovich Rodionov,Alexander Borisovich Tuzikov
申请号:
US13984050
公开号:
US20140161723A1
申请日:
2012.02.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Functional-lipid constructs of the structure F-S-L are disclosed, wherein F comprises a tyrosine or histidine residue, S is a spacer covalently linking F to L and L is a lipid. The functional residue may be iodinated and used to radiolabel a biological entity with 1251 and the iodinated constructs are used in a non-invasive method of monitoring the distribution of a biological entity in vivo.