“LINEAR EXPRESSION CONSTRUCTS FOR PRODUCTION OF INFLUENZA VIRUS PARTICLES”

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专利权人:

AVIR GREEN HILLS BIOTECHNOLOGY RESEARCH DEVELOPMENT TRADE AG

发明人:

WOLSCHEK  MARKUS,EGOROV&NBSP,ANDREJ,BERGMANN&NBSP,MICHAEL,MUSTER&NBSP,THOMAS,KITTEL&NBSP,CHRISTIAN

申请号：

IN4355KON2009

公开号：

IN4355KON2009A

申请日:

2009.12.16

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

The present invention provides a linear expression construct free of any conventional amplification and/or selection sequences comprising an RNA polymerase I (poll) promoter and a poll termination signal, inserted between a RNA polymerase Il (polll) promoter and a polyadenylation signal useful for the expression of segments of viral RNA, preferably influenza viruses. The inventive construct is useful for efficient and fast production of viral particles, especially for producing vaccine formulations for the treatment of epidemic and/or pandemic diseases.

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http://www.ckcest.cn/home/