AVIR GREEN HILLS BIOTECHNOLOGY RESEARCH DEVELOPMENT TRADE AG
发明人:
KITTEL, CHRISTIAN,MUSTER, THOMAS,BERGMANN, MICHAEL,EGOROV, ANDREJ,WOLSCHEK, MARKUS
申请号：
NZ58210208
公开号：
NZ582102A
申请日:
2008.06.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed is a linear expression construct free of any conventional amplification and/or selection sequences comprising an RNA polymerase I (poll) promoter and a poll termination signal, inserted between a RNA polymerase Il (polll) promoter and a polyadenylation signal useful for the expression of segments of viral RNA, preferably influenza viruses. The inventive construct is useful for efficient and fast production of viral particles, especially for producing vaccine formulations for the treatment of epidemic and/or pandemic diseases.
