Muster, Thomas,Wolschek, Markus,Bergmann, Michael,Egorov, Andrej,Kittel, Christian
申请号：
AU2008267180
公开号：
AU2008267180B2
申请日:
2008.06.26
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention provides a linear expression construct free of any conventionalamplification and/or selection sequences comprising an RNA polymerase I (poll)promoter and a poll termination signal, inserted between a RNA polymerase Il(polll) promoter and a polyadenylation signal useful for the expression of segmentsof viral RNA, preferably influenza viruses. The inventive construct is usefulfor efficient and fast production of viral particles, especially for producingvaccine formulations for the treatment of epidemic and/or pandemic diseases.
