Jorge R. Barrio,Vladimir Kepe,Gary W. Small,Nagichettiar Satyamurthy
申请号:
US12594197
公开号:
US08372380B2
申请日:
2008.03.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with 18F, 123I, 124I, 125I, or 11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.