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IN VIVO IMAGING OF SULFOTRANSFERASES
专利权人:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
BARRIO, JORGE, R.,KEPE, VLADIMIR,SMALL, GARY, W.,SATYAMURTHY, NAGICHETTIAR
申请号:
EP08742427
公开号:
EP2171478A4
申请日:
2008.03.31
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with 18F, 123I, 124I, 125I, or 11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.
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