INHIBITEURS SUBSTITUES DE MENINE-MLL ET METHODES D'UTILISATION

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专利权人:

INC.;THE REGENTS OF THE UNIVERSITY OF MICHIGAN;KURA ONCOLOGY, INC.;KURA ONCOLOGY

发明人:

WU, TAO,LI, LIANSHENG,WANG, YI,REN, PINGDA,GREMBECKA, JOLANTA,CIERPICKI, TOMASZ,KLOSSOWSKI, SZYMON,POLLOCK, JONATHAN,BORKIN, DMITRY

申请号：

CA3015847

公开号：

CA3015847A1

申请日:

2017.03.15

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present disclosure provides methods of inhibiting the interaction of menin with MLLl, MLL2 and MLL-fusion oncoproteins. The methods are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLLl, MLL2, MLL fusion proteins, and/or menin. Compositions for use in these methods are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/