KURA ONCOLOGY INC.;THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人:
申请号:
IL26162518
公开号:
IL261625D0
申请日:
2018.09.05
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
The present disclosure provides methods of inhibiting the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The methods are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin. Compositions for use in these methods are also provided.