METHODS AND COMPOSITIONS FOR INHIBITING THE INTERACTION OF MENIN WITH MLL PROTEINS

• 收藏
• 分享

专利权人:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN;KURA ONCOLOGY, INC.

发明人:

GREMBECKA, Jolanta,BORKIN, Dmitry,CIERPICKI, Tomasz,POLLOCK, Jonathan,LI, Liansheng,WU, Tao,FENG, Jun,REN, Pingda,LIU, Yi,KLOSSOWSKI, Szymon

申请号：

PH12017502188

公开号：

PH12017502188A1

申请日:

2017.11.29

申请国别(地区):

PH

年份:

2018

代理人:

摘要：

The present disclosure provides compositions and methods of use to inhibit the interaction of menin with MLLl, MLL2 and MLL-fusion oncoproteins. The compositions and methods of use are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLLl, MLL2, MLL fusion proteins, and/or menin.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/