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Methods and compositions for inhibiting the interaction of menin with MLL proteins
专利权人:
Inc.;The Regents of the University of Michigan;Kura Oncology, Inc.;Kura Oncology
发明人:
Grembecka, Jolanta,Borkin, Dmitry,Cierpicki, Tomasz,Pollock, Jonathan,Li, Liansheng,Wu, Tao,Feng, Jun,Ren, Pingda,Liu, Yi,Klossowski, Szymon
申请号:
AU2016270002
公开号:
AU2016270002A1
申请日:
2016.03.16
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present disclosure provides compositions and methods of use to inhibit the interaction of menin with MLLl, MLL2 and MLL-fusion oncoproteins. The compositions and methods of use are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLLl, MLL2, MLL fusion proteins, and/or menin.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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