Heterocyclic compounds derived from etinilo, mGluR5 allosteric modulators； Preparation Process； Pharmaceutical composition； use in the Prevention or treatment of Cognitive diseases, Schizophrenia, Autism or Fragile X Syndrome.
The present invention relates to ethynyl derivatives of formula I wherein U, V, Y, R1, R2, R2&prime；, R3, R3&prime； and R8 are described herein. It has been found that the compounds of general formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).COMPUESTOS HETEROCICLICOS DERIVADOS DE ETINILO-PIRIDINA(PIRIMIDINA), MODULADORES ALOSTERICOS DE MGLUR5； PROCESO DE PREPARACION； COMPOSICION FARMACEUTICA； USO EN LA PREVENCION O EL TRATAMIENTO DE ESQUIZOFRENIA, ENFERMEDADES COGNITIVAS, SINDROME DE LA X FRAGIL O AUTISMO.
