PROBLEM TO BE SOLVED: To provide pharmaceuticals, food and the like that inhibit the degradation of articular cartilage and are useful for prevention or improvement of arthropathy caused by the degradation of articular cartilage.SOLUTION: An articular cartilage degradation inhibitor contains ellagic acid or a derivative thereof or a salt thereof in combination with catechin.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】関節軟骨の分解を抑制し、関節軟骨の分解に起因する関節障害の予防又は改善に有用な、医薬品、食品等を提供する。【解決手段】エラグ酸若しくはその誘導体又はそれらの塩とカテキン類を組み合わせてなる関節軟骨分解抑制剤。【選択図】なし