4R,5S-ENANTIOMER 2-(5-METIL-2-OKSO-4-FENIL-PIROLIDIN-1-IL)-ACETAMIDA Z NOOTROPIÄŚNO AKTIVNOSTJO

• 收藏
• 分享

专利权人:

A JOINT STOCK COMPANY;GRINDEKS

发明人:

KALVINS IVARS,LEBEDEVS ANTONS,CERNOBROVIJS ALEKSANDRS,DAMBROVA MAIJA,ZVEJNIECE LIGA,VORONA MAKSIMS,VEINBERGS GRIGORIJS,KALVINS Ivars,LEBEDEVS Antons,CERNOBROVIJS Aleksandrs,DAMBROVA Maija,ZVEJNIECE Liga,VORONA Maksims,VE

申请号：

SI201030416

公开号：

SI2496555T1

申请日:

2010.11.04

申请国别(地区):

SI

年份:

2013

代理人:

摘要：

The invention relates to the 5S,4R-enantiomer of 2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide with cognition enhancing activity of high pharmacological value and to its preparation method which includes the synthesis of 5S-methyl-4R-phenylpyrrolidin-2-one, its N-alkylation with ethyl haloacetate and the treatment of intermediate ethyl 2-(5S-methyl-2-oxo-4R-phenyl-pyrrolidin-1-yl)-acetate with ammonia.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/