ENANTIOMERE 4R,5S DE 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE AYANT UNE ACTIVITE NOOTROPIQUE
- 专利权人:
- GRINDEKS; A JOINT STOCK COMPANY
- 发明人:
- KALVINS, IVARS,LEBEDEVS, ANTONS,CERNOBROVIJS, ALEKSANDRS,DAMBROVA, MAIJA,ZVEJNIECE, LIGA,VORONA, MAKSIMS,VEINBERGS, GRIGORIJS
- 申请号：
- CA2780040
- 公开号：
- CA2780040C
- 申请日:
- 2010.11.04
- 申请国别(地区):
- CA
- 年份:
- 2014
- 代理人:
- 摘要：
- The invention relates to the 5S,4R-enantiomer of 2-(5-methyl-2-oxo-4-phenyl- pyrrolidin-1-yl)-acetamide with cognition enhancing activity of high pharmacological value and to its preparation method which includes the synthesis of 5S-methyl-4R-phenylpyrrolidin-2-one, its N-alkylation with ethyl haloacetate and the treatment of intermediate ethyl 2-(5S-methyl-2-oxo-4R-phenyl-pyrrolidin-1-yl)-acetate with ammonia.
- 来源网站：
- 中国工程科技知识中心
相关发明人
相关专利
- 4R, 5S ENANTIOMES OF 2- (5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL) -ACETAMIDE WITH NOOTROPIC ACTIVITY
- 4R,5R-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY
- ENANTIOMÈRE 4R,5R DU 2-(5-MÉTHYL-2-OXO-4-PHÉNYLPYRROLIDINE-1-YL) ACÉTAMIDE À ACTIVITÉ NOOTROPIQUE
- DIFFERENT PHARMACEUTICAL FORM OF CAPITAL [(1S)-1-{[(2S,4R)-4-(7-XLOPO-4-methoxy-isoquinoline-1-hydroxy)-2-({(1R, 2-YYTHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHE1,1,1,1-1-THETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHETHEmethylmethylmethylmethylmethylmethylmethylmethylmethylmethylmethy
- THYMOQUINONE/HARMALINE ET PRODUITS DE RÉACTION APPARENTÉS
