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Dérivés de pleuromutilin
专利权人:
NABRIVA THERAPEUTICS AG
发明人:
申请号:
EP08772584.2
公开号:
EP2176211B1
申请日:
2008.07.11
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
A compound of formula (I) wherein Y is oxygen or sulfur, and X 1 , X 2 and X 3 are independently hydrogen, halogen, hydroxy or linear or branched (C 1-6 )alkyl, or hydroxy-(C 1-6 )alkyl or (C 1-6 )alkoxy-(C 1-6 )alkyl, mono- or dihalogenated (C 1-6 )alkyl, amino-(C 1-6 )alkyl, hydroxy-(C 1-6 )alkyl, with the provisos that (1) at least one of X 1 , X 2 and X 3 is not hydrogen, and (2) X 2 is not hydroxy when X 1 and X 3 are hydrogen are useful in the treatment of diseases mediated by microbes.
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