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ANTICANCER FUSION PROTEIN
专利权人:
ADAMED SP.Z O.O
发明人:
PIECZYKOLAN JERZY SZCZEPAN,LEMKE KRZYSZTOF KAZIMIERZ,PAWLAK SEBASTIAN DOMINIK,ZEREK BARTLOMIEJ
申请号:
ZA201303449
公开号:
ZA201303449B
申请日:
2013.05.13
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and domain (b) which is a sequence of an immunostimulating effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
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