PIECZYKOLAN, JERZY SZCZEPAN,PAWLAK, SEBASTIAN,ZEREK, BARTLOMIEJ,LEMKE, KRZYSZTOF KAZIMIERZ
申请号:
DK11790636
公开号:
DK2646464T3
申请日:
2011.12.05
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and domain (b) which is a sequence of an immunostimulating effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.