Pieczykolan, Jerzy Szczepan,Lemke, Krzysztof Kazimierz,Pawlak, Sebastian,Zerek, Bartlomiej
申请号:
AU2011334868
公开号:
AU2011334868A1
申请日:
2011.12.05
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and domain (b) which is a sequence of an immunostimulating effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a).The fusion protein can be used for the treatment of cancer diseases.