BARTLOMIEJ ZEREK,JERZY SZCZEPAN PIECZYKOLAN,KRZYSZTOF KAZIMIERZ LEMKE,SEBASTIAN PAWLAK
申请号：
BR112013013548
公开号：
BR112013013548A2
申请日:
2011.12.05
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity； and domain (b) which is a sequence of an immunostimulating effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
