SHOWALTER, Richard,ALMASSY, Robert,THOMSON, James A.,SISSON, Wes,SHIA, Wei-Jong,CHEN, Li-Chang,LEE, Yang
申请号：
EP15842576
公开号：
EP3193913A4
申请日:
2015.09.16
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.
