SHOWALTER, RICHARD,ALMASSY, ROBERT,THOMSON, JAMES A.,SISSON, WES,SHIA, WEI-JONG,CHEN, LI-CHANG,LEE, YANG
申请号：
CA2961602
公开号：
CA2961602A1
申请日:
2015.09.16
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.
