HYUN, CHANG GU,현창구,KIM, MIN JIN,김민진,MOON, JI YOUNG,문지영,KIM, JUNG EUN,김정은,KIM, HYOUN,김현,KIM, JEONG MI,김정미,YANG, KYONG WORL,양경월
申请号：
KR1020110126758
公开号：
KR1020130060611A
申请日:
2011.11.30
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: An anti-inflammatory composition using a Citrus unshiu flower extract is provided to suppress NO, iNOS, COX-2, inflammatory cytokine, and PGE2 generation. CONSTITUTION: An anti-inflammatory composition contains a Citrus unshiu flower extract as an active ingredient. The extract is selected among: an extract which is prepared by dipping and extracting Citrus unshiu flowers in 70-90% ethanol solution； a hot water extract which is prepared by dipping Citrus unshiu flowers in water； an extract which is prepared by distilling Citrus unshiu flowers with water； and an ethyl acetate fraction or a water fraction which is prepared by dipping Citrus unshiu flowers in 70-90% ethanol solution, and fractioning the extract with ethyl acetate and water.본 발명은 온주 밀감 꽃 추출물을 이용한 항염증제 조성물을 개시한다. 구체적으로 본 발명은 NO 생성 억제 활성, iNOS 및 COX-2 생성 억제 활성, 염증성 사이토카인의 생성 억제 활성 및 PGE2의 생성 억제 활성을 가지는 온주 밀감 꽃 추출물을 이용한 항염증제 조성물을 개시한다.
