FORME CRISTALLINE DE (R)-1(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-MÉTHYLPROPAN-2-YL)-1H-INDOL-5-YL)CYCLOPROPANECARBOXAMIDE

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

申请号：

EP11713134.2

公开号：

EP2563778B1

申请日:

2011.03.25

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention relates to solid amorphous form of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (compound 1), pharmaceutical compositions thereof, solid dispersions thereof and the compound 1 for use in the treatment of a CFRT mediated diseases such as cytosic fibrosis

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