This invention makes public that the five crystal forms of XLF-III-43 [3-(3'-carboxy-4'-hydroxy-anilino-carbo-)-6-nitro-7-hydroxy-8-methyl-coumarin)] can be used ascrude drugs, refers to the preparing methods of the five crystal forms of XLF-III-43 ascrude drugs, refers to applying the sterling of the five crystal forms of XLF-III-43and mixed crystals with different proportions as medicine active components todevelop all kinds of medicines and compound medicines. In addition, thisinvention alsorefers to applying the crystal samples of XLF-III-43 as crude drugs to treatkidneydysfunction, cardiocerebral vessel diseases, hypertension, type II diabeticmellitus,complications of hypertension and diabetic mellitus, tumor, precancerosis,edema , andbring therapeutic effects by enhancing blood drug levels resulted from effectsof crystalforms in the processes of treating all kinds of diseases.
