polysubstituted azetidine compounds, their preparation and their therapeutic application.

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专利权人:

SANOFI-AVENTIS

发明人:

CORINNE TERRIER,FLORIAN AUGER,JEAN-FRANÇOIS SABUCO,PATRICK BERNARDELLI

申请号：

BRPI0917944

公开号：

BRPI0917944A2

申请日:

2009.08.13

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The invention relates to compounds of the formula (I) where: R is a (C1-C6)alkyl group, a halo(C1-C6)alkyl group； R1 is a hydrogen atom； R2 is a heterocyclic group bound by a carbon atom, a heterocyclic-(C1-C4)alkyl group, said groups being optionally substituted； R3 and R4 represent independently from each other an optionally substituted phenyl group； X is a hydrogen atom, a halogen, a cyano, a (C1-C6)alkyl group, a halo(C1-C6)alkyl group, a (C1-C6)alkoxy group, a halo(C1-C6)alkoxy group or a (C1-C6)alkylS(0)p group； and p is 0 to 2. The invention also relates to a method for preparing same and to the therapeutic application thereof.

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