Providing an AdipoR activator that activates both AdipoR1 and AdipoR2. The following general formula (1): wherein A is a substituted or unsubstituted aryl group, Y1 is (CHR2) a-, X is CH or N, R1 is a C1-7 alkyl group, m is 0-4 Integer, Y2 is * -O-CH2-CONH-, * -CONH- (CH2) b-CO-, etc., Z is a cyclic group, B is a group that can be substituted with a cyclic group represented by Z, n is 0 An integer of ~ 3. ] The compound represented by this.AdipoR1及びAdipoR2の両方を活性化させる、AdipoRのアクチベーターの提供。 下記一般式(1)〔式中、Aは置換又は非置換のアリール基等、Y1は(CHR2)a-等、XはCH又はN、R1はC1~7アルキル基、mは0~4の整数、Y2は、*-O-CH2-CONH-、*-CONH-(CH2)b-CO-等、Zは環状基、Bは、Zで示される環状基に置換し得る基、nは0~3の整数。〕で表される化合物。