Tomá{hacek over (s)} Andrýsek;Ale{hacek over (s)} Vrána;Alexandr Jegorov;Richard Szrajber
发明人:
Ale{hacek over (s)} Vrána,Tomá{hacek over (s)} Andrýsek,Alexandr Jegorov,Richard Szrajber
申请号：
US10516904
公开号：
US08895059B2
申请日:
2003.06.05
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to compositions and methods for reducing cross-linking in the gelatin shell of gelatin capsules by incorporation of free amino acid into the capsule shell and by inclusion of an ester of carboxylic acid either into the capsule filling, and/or into the capsule shell and/or into the lubrication agent, or in combinations thereof. Described are soft gelatin capsules characterized by improved stability as compared with gelatin capsules that do not contain amino acid in the shell and carboxylic acid ester in the filling, shell or in the lubrication agent, or in combinations thereof.
