ENDOCYTE, INC.;PURDUE RESEARCH FOUNDATION;SEATTLE CHILDREN'S HOSPITAL (DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE)
发明人:
Philip Stewart LOW,Haiyan CHU,Yingjuan June LU,Christopher Paul LEAMON,Leroy W. WHEELER, II,Michael C. JENSEN,James MATTHAEI
申请号:
US16253562
公开号:
US20190255109A1
申请日:
2019.01.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.