Seattle Children's Hospital (dba Seattle Children's Research Institute)
发明人:
Michael C. Jensen,James Matthaei
申请号:
US16253572
公开号:
US20190224237A1
申请日:
2019.01.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.