Purdue Research Foundation;Seattle Children's Hospital (DBA Seattle Children's Research Institute);Endocyte, Inc.
发明人:
LOW, Philip Stewart,CHU, Haiyan,LU, Yingjuan June,LEAMON, Christopher Paul,WHEELER II, Leroy W.,JENSEN, Michael C.,MATTHAEI, James
申请号:
AU2019209428
公开号:
AU2019209428A1
申请日:
2019.01.22
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.