SEATTLE CHILDREN'S HOSPITAL (DBA SEATTLE CHILDREN'S RESEARCH INSTITUTE)
发明人:
JENSEN, Michael C.,MATTHAEI, James,LOW, Philip S.,CHU, Haiyan,LU, Yingjuan J.,LEAMON, Christopher P.,WHEELER, Leroy
申请号:
SG11202006886V
公开号:
SG11202006886VA
申请日:
2019.01.22
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.