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CALICHEAMICIN DERATIVES AND ANTIBODY DRUG CONJUGATES THEREOF
专利权人:
PFIZER INC.
发明人:
Omar Khaled Ahmad,Stephen Paul Brown,Kenneth John Dirico,Russell Dushin,Gary Frederick Filzen,Sujiet Puthenveetil,Pavel Strop,Chakrapani Subramanyam,Lawrence N. Tumey
申请号:
US16477290
公开号:
US20190345186A1
申请日:
2018.01.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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