PFIZER INC.;Omar Khaled AHMAD;Stephen Paul BROWN;Kenneth John DIRICO;Russell DUSHIN;Gary Frederick FILZEN;Sujiet PUTHENVEETIL;Pavel STROP;Chakrapani SUBRAMANYAM;Lawrence N. TUMEY
发明人:
Omar Khaled AHMAD,Stephen Paul BROWN,Kenneth John DIRICO,Russell DUSHIN,Gary Frederick FILZEN,Sujiet PUTHENVEETIL,Pavel STROP,Chakrapani SUBRAMANYAM,Lawrence N. TUMEY
申请号:
IL26824519
公开号:
IL268245D0
申请日:
2019.07.24
申请国别(地区):
IL
年份:
2019
代理人:
摘要:
The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.