Dirico, Kenneth John,Dushin, Russell,Filzen, Gary Frederick,Puthenveetil, Sujiet,Strop, Pavel,Subramanyam, Chakrapani,Tumey, Lawrence N.,Ahmad, Omar Khaled,Brown, Stephen Paul
申请号:
AU2018211561
公开号:
AU2018211561A1
申请日:
2018.01.10
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.