Imelda OLIVAS ARMENDÁRIZ,Laura Elizabeth VALENCIA GOMEZ,Santos Adriana MARTEL ESTRADA
申请号：
MX2016007284
公开号：
MX2016007284A
申请日:
2016.06.03
申请国别(地区):
MX
年份:
2017
代理人:
摘要：
The present disclosure is related to the biomaterials manufacturing process for the skin wounds treatment. The composition of the invention contains a polymer that is obtained from chitosan, carboxymethyl chitosan being presented in the form of a thin film, also water soluble, as well as providing the following properties to the invention: biocompatibility, exudates absorption and biodegradability containing glycerol as a natural plasticizing agent and genipin as a polymeric crosslinker for the improvement of the biomaterial physical properties. In addition, a therapeutic amount of the Mimosa tenuiflora plant ethanolic extract is provided, acting as a promoter and an accelerator to heal skin superficial wounds, either chronic or acute, with possible tendency to bacterial infections. A process is also included for manufacturing a biodegradable film made of Carboxymethyl Chitosan and Mimosa tenuiflora Ethanolic extract, comprising the following stages: 1.1 1.2 1.3 1.4 1.5 1.6 1. 7 1.8 as well as glycerol and genipin as secondary ingredients. Finally, the composite dressing described above, can be used for the promotion and repair of wounds, ulcers or skin burns.La inv3ención descrita proprciona la elaboración de biomateriales para el tratamiento de heridas en la piel. La composición de la invención contiene un polímero obtenido a partir del quitosano, el carboximetil quitosano, el cual se presenta en forma de película delgada, siendo soluble en agua además de proporcionar las propiedades de biocompatibilidad, absorción de exudados y biodegradabilidad a la invención conteniendo glicerol como agente plastificante natural y genipina como un entrecruzante polimérico, para el mejoramiento de las propiedades físicas del biomaterial. Además, se comprende de una cantidad terapéutica del extracto etanólico de la planta de Mimosa tenuiflora como promotor y acelerador de la cicatrización de heridas superficiales en piel, ya sea crónicas o agudas, con posible tendencia a infeccio
