MICKLE TRAVIS,GUENTHER SVEN,BERA SANJIB,KANSKI JAROSLAW,MARTIN ANDREA
申请号：
IN201747018906
公开号：
IN201747018906A
申请日:
2017.05.30
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The presently described technology provides compositions comprising aryl carboxylic acids and for example NSAIDs chemically conjugated to oxymorphone (4 5 a epoxy 3 14 dihydroxy 17 methylmorphinan 6 one) to form novel prodrugs/compositions of oxymorphone including benzoates salicylates propionates fenamates and acetates which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients pharmaceutical kits and methods of synthesizing conjugates of the present technology.
