APTAMERS SPECIFIC FOR TLR 4 AND USES THEREOF

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专利权人:

发明人:

LIZASOAIN HERNÃNDEZ IGNACIO,GONZÁLEZ MUÑOZ VÃCTOR MANUEL,FERNÁNDEZ GÓMEZ CHACÓN GERóNIMO,MORO SÃNCHEZ MARà A ÃNGELES,MARTÃN PALMA Mª ELENA,MORAGA YÉBENES ANA

申请号：

IN201617043688

公开号：

IN201617043688A

申请日:

2016.12.21

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The invention relates to a nucleic acid aptamer with the capability of binding specifically to and inhibiting TLR-4 to a complex comprising said aptamer and a functional group as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/