The invention relates to polypeptides which enable the specific targeting of a molecule of interest to homeoprotein Otx2 target cells. These polypeptides are defined by the general sequence: B1B2X1B3B4X2B5X3X4X5X6B6X7X8X9 (SEQ ID NO: 1), in which: B1, B2, B3, B4, B5 and B6are independently arginine or lysine; X1 and X8 are independently asparagine or glutamine; X2 is aspartic acid or glutamic acid; X3, X4 and X6 are independently threonine or serine; X5 is phenylalanine, tyrosine or tryptophan; X7 represents alanine or glycine; X9 is leucine, isoleucine or valine.