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FVIII-DERIVED PEPTIDES AND THEIR USE IN TOLERISING HAEMOPHILIACS
专利权人:
发明人:
申请号:
HK12112448.9
公开号:
HK1172240A
申请日:
2012.12.03
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
The present invention provides peptides at least partly derivable from FVIII which are capable of binding to an MHC class II molecule without further antigen processing and being recognised by a factor VIII specific T cell. In particular, the present invention provides a peptide comprising or consisting of the sequence EDNIMVTFRNQASR. The present invention also relates to the use of such a peptide for the prevention or suppression of inhibitor antibody formation in haemophilia A and/or acquired haemophilia.
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中国工程科技知识中心
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