FVIII-derived peptide

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专利权人:

アピトープ インターナショナル エヌブイ

发明人:

ライス， デイビッド,ライス, デイビッド

申请号：

JP2012511336

公开号：

JP5784009B2

申请日:

2010.05.17

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The present invention provides peptides at least partly derivable from FVIII which are capable of binding to an MHC class II molecule without further antigen processing and being recognised by a factor VIII specific T cell. In particular, the present invention provides a peptide comprising or consisting of the sequence EDNE 4VTFRNQASR. The present invention also relates to the use of such a peptide for the prevention or suppression of inhibitor antibody formation in haemophilia A and/or acquired haemophilia.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/