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FVIII -DERIVED PEPTIDES
专利权人:
APITOPE TECHNOLOGY (BRISTOL)LIMITED
发明人:
申请号:
IL21619911
公开号:
IL216199D0
申请日:
2011.11.07
申请国别(地区):
IL
年份:
2012
代理人:
摘要:
The present invention provides peptides at least partly derivable from FVIII which are capable of binding to an MHC class II molecule without further antigen processing and being recognised by a factor VIII specific T cell. In particular, the present invention provides a peptide comprising or consisting of the sequence EDNE 4VTFRNQASR. The present invention also relates to the use of such a peptide for the prevention or suppression of inhibitor antibody formation in haemophilia A and/or acquired haemophilia.
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中国工程科技知识中心
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