YAN, JIAN,SLAGER, ANNA,GARMAN, BRADLEY,COOCH, NEIL
申请号:
CA3084137
公开号:
CA3084137A1
申请日:
2018.12.13
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus LEMDl antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus LEMDl antigen are disclosed. Methods of treating a subject with a LEMDl -expressing tumor and methods of preventing a LEMDl -expressing tumor are disclosed. Mutated consensus LEMDl antigen is disclosed.