THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;INOVIO PHARMACEUTICALS, INC.
发明人:
WEINER, DAVID B.,YAN, JIAN,WALTERS, JEWELL
申请号：
CA2888648
公开号：
CA2888648A1
申请日:
2013.12.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated WT1 antigen. Vectors, compositions and vaccines comprising one or more nucleic acid sequences that encode a mutated WT1 antigen are disclosed. Methods of treating an individual who has a WT1-expressing tumor and methods of preventing a WT1-expressing tumor are disclosed. Mutated WT1 antigen is disclosed.
