The Trustees of the University of Pennsylvania;Inovio Pharmaceuticals, Inc.
发明人:
David B. Weiner,Jian Yan,Jewell Walters
申请号：
US16221707
公开号：
US20190255163A1
申请日:
2018.12.17
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated WT1 antigen. Vectors, compositions and vaccines comprising one or more nucleic acid sequences that encode a mutated WT1 antigen are disclosed. Methods of treating an individual who has a WT1-expressing tumor and methods of preventing a WT1-expressing tumor are disclosed. Mutated WT1 antigen is disclosed.
