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KIDNEY-TARGETED EPOXYEICOSATRIENOIC ACID (EET) ANALOGS
专利权人:
THE MEDICAL COLLEGE OF WISCONSIN; INC.
发明人:
John D. Imig,John R. Falck,Abdul Hye Khan,Adeniyi ADEBESIN
申请号:
US16647603
公开号:
US20200255433A1
申请日:
2018.09.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Described here are EET analogs conjugated to folate receptor ligands such as folic acid or folic acid analogs recognized by and selectively bound by folate receptors and other folate binding proteins and the use of such conjugated EET analogs for targeted delivery of therapeutic agents to folate-receptor bearing cell populations. More particularly, provided herein are EET analogs conjugated to folate receptor ligands and uses of such conjugated EET analogs as kidney targeted therapeutics.
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