IMIG, JOHN D.,FALCK, JOHN R.,KHAN, ABDUL HYE,ADEBESIN, ADENIYI
申请号:
CA3075755
公开号:
CA3075755A1
申请日:
2018.09.14
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Described here are EET analogs conjugated to folate receptor ligands such as folic acid or folic acid analogs recognized by and selectively bound by folate receptors and other folate binding proteins and the use of such conjugated EET analogs for targeted delivery of therapeutic agents to folate-receptor bearing cell populations. More particularly, provided herein are EET analogs conjugated to folate receptor ligands and uses of such conjugated EET analogs as kidney targeted therapeutics.