Folate mimetics and folate-receptor binding conjugates thereof

• 收藏
• 分享

专利权人:

Mark A Green

发明人:

Mark A Green,Chun-Yen Ke,Christopher P Leamon

申请号：

US12775824

公开号：

US08470822B2

申请日:

2010.05.07

申请国别(地区):

US

年份:

2013

代理人:

摘要：

This present disclosure relates to folate mimetics and their use in therapeutic and diagnostic applications. More particularly, the disclosure relates to using des-glutamyl folic acid analogs recognized by and selectively bound by folate receptors and other folate binding proteins and the use of such analogs for targeted delivery of diagnostic or therapeutic agents to folate-receptor bearing cell populations.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/