The invention is directed to a method for increasing phosphatidylcholine in the blood of a subject comprising administering to the subject a composition having uridine or a metabolic precursor of uridine choline or a metabolic precursor of choline and at least one omega-3 fatty acid and/or omega-6 fatty acid, the phosphatidylcholine has a glycerol portion and the glycerol portion is bonded to two fatty acids and the total amount of carbons in the fatty acids is about 16 to 40 carbon atoms.