Disclosed is the use of (a) an omega-3 fatty acid, an omega-6 fatty acid, or a combination thereof； (b) uridine, an acyl derivative thereof, a uridine phosphate or a CDP-choline； and (c) choline, a choline salt, or a precursor thereof, wherein the choline is present in an amount of about 150mg to 8g, in the manufacture of a composition for treating a cognitive or neurological disorder in a subject, provided said composition is not human breast milk, and said cognitive or neurological disorder is not Alzheimer's disease, memory impairment or memory loss. Further disclosed is a composition comprising: (a) an omega-3 fatty acid, an omega-6 fatty acid or a combination thereof； (b) a uridine, an acyl derivative thereof, a uridine phosphate； or a CDP-choline； and (c) a choline salt, wherein choline is present in an amount of about 150mg to 8g, and said composition is not human breast milk. Additionally,
